The cumulative case count passed 12 million on Saturday, six days after the previous million mark was crossed, which was six days after the previous million.
On Friday alone, there were more than 195,000 new confirmed cases and 1,878 deaths reported, according to data from Johns Hopkins University.
More than 255,000 people have died in total, as of Saturday afternoon.
And more than 1,000 hospitals, across all 50 states, Washington, D.C., and Puerto Rico, say they are "critically" short on staff, according to the Department of Health and Human Services. And that number is expected to increase after the holidays.
To avoid an even starker increase in the spread of the virus, the Centers for Disease Control and Prevention is urging people to not travel for Thanksgiving at all. The CDC says Thanksgiving should be spent only with people actively living in your own household for at least 14 days before the holiday, advice many medical professionals are echoing.
"Travel may increase your chance of getting and spreading COVID-19," the CDC said on Thursday. "Postponing travel and staying home is the best way to protect yourself and others this year."
Meanwhile, two COVID-19 vaccines appear to be highly effective. The first, created by pharmaceutical company Pfizer and its partner BioNTech, is reported as being 95% effective. The second, created by the biotech company Moderna Inc., has been reported as being 94.5% effective.